রবিবার, ৩০ জুন, ২০১৩

White Makes First Cut For World University Games

Incoming Iowa junior Aaron White was named one of 16 finalists for the U.S.A. World Men?s World University Games roster.

Tryouts continue for the 12-member squad through June 30. The team leaves for Kazan, Russia on July 1 with competition held July 7-16. Iowa guard Devyn Marble, who also tried out for the team, was not named a finalist.

White, a 6-foot-8 forward, was named third-team all-Big Ten and led Iowa in rebounding (6.2), the first Hawkeye to lead the team in rebounding as a freshman and sophomore since Michael Payne in 1981-82. He ranked second on the team in scoring (12.8) and steals (41). White made (193) and attempted (258) the most free throws of any sophomore in Iowahistory. In two seasons, White has scored 877 career points.

Four Big Ten players are listed as finalists: White, Adreian Payne (Michigan State), Yogi Ferrell (Indiana) and Will Sheehey (Indiana). Marble, Andre Hollins (Minnesota) and A.J. Hammons (Purdue) were not selected as finalists.

Other finalists include: Spencer Dinwiddie (Colorado); Davante Gardner (Marquette); Treveon Graham (Virginia Commonwealth); Jerian Grant(Notre Dame); Luke Hancock (Louisville); Tyler Haws (BYU); Rodney Hood (Duke); Cory Jefferson (Baylor); Sean Kilpatrick (Cincinnati); Alex Kirk (New Mexico); Doug McDermott (Creighton); Chasson Randle (Stanford).

Source: http://www.kcrg.com/sports/hawkeyes/White-Makes-First-Cut-For-World-University-Games-213258201.html

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Biomarker predicts risk of breast cancer recurrence after tamoxifen treatment

June 29, 2013 ? A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment. In their report being published online in the Journal of the National Cancer Institute, Massachusetts General Hospital (MGH) Cancer Center investigators describe finding that the HOXB13/IL17BR ratio can indicate which women are at risk for cancer recurrence after tamoxifen and which are most likely to benefit from continuing treatment with the aromatase inhibitor letrozole (Femara).

"Most patients with early-stage, ER-positive breast cancer remain cancer-free after five years of tamoxifen treatment, but they remain at risk of recurrence for 15 years or longer after their initial treatment," says Dennis Sgroi, MD, of the MGH Cancer Center and Department of Pathology, lead and corresponding author of the report. "Our biomarker identifies the subgroup of patients who continue to be at risk of recurrence after tamoxifen treatment and who will benefit from extended therapy with letrozole, which should allow many women to avoid unnecessary extended treatment."

Previous research by Sgroi's team, in collaboration with investigators from bioTheranostics Inc., discovered that the ratio between levels of expression of two genes -- HOXB13 and IL17BR -- in tumor tissue predicted the risk of recurrence of ER-positive, lymph-node-negative breast cancer, whether or not the patient was treated with tamoxifen. The current study of patients from MA.17, the highly successful clinical trial of letrozole, was designed to evaluate the usefulness of the HOXB13/IL17BR ratio for both prognosis -- predicting which tamoxifen-treated remained patients at risk of recurrence -- and for identifying who could benefit from continued treatment with letrozole.

To answer those questions the investigators analyzed primary tumor samples and patient data from the placebo-controlled MA.17 trial, which confirmed the ability of extended letrozole therapy to improve survival after the completion of tamoxifen treatment. Tissue samples were available from 83 patients whose tumors recurred during the study period -- 31 who had received letrozole and 52 in the placebo group -- and 166 patients with no recurrence, 91 of whom had received letrozole, with 75 getting the placebo. Analysis of the tumor samples revealed that a high HOXB13/IL17BR ratio -- meaning the expression level of HOXB13 is greater than that of IL17BR -- predicts an increased risk for tumor recurrence after tamoxifen therapy, but that elevated risk drops significantly if a patient receives letrozole

Paul E. Goss, MD, PhD, director of the Breast Cancer Research Program at the MGH Cancer Center and a co-author of the report, explains, "This discovery means that about 60 percent of women with the most common kind of breast cancer can be spared unnecessary treatment with the concommitant side effects and costs. But more importantly, the 40 percent of patients who are at risk of recurrence can now be identified as needing continued therapy with letrozole, and many will be spared death from breast cancer." He and Sgroi note that their findings need to be validated by additional studies before they can be put into clinical practice.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/kFmW4R0U9Fo/130629164733.htm

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শনিবার, ২৯ জুন, ২০১৩

NASA Space Shuttle Runway Gets New Life as Commercial Spaceport

CAPE CANAVERAL, Fla. ? The famous?seaside?space shuttle runway here at NASA's Kennedy Space Center may have a second life soon as a launch and landing spot for a whole new type of space mission: tourist flights.

The 15,000-foot-long (4,600 meters)?Shuttle Landing Facility (SLF) has been unused for spaceflights since the 30-year space shuttle program retired in 2011. But now NASA is handing over operation of the facility to Space Florida, the aerospace economic development agency for the state of Florida, to put the runway to new uses.

"Space Florida will take over operation of SLF as a combined airport and spaceport," NASA administrator Charles Bolden said here at a press conference today (June 28). "This will continue to expand Kennedy's viability as a multiuser spaceport. We look forward to working with Space Florida over the coming months." [Photos: NASA's Last Shuttle Landing in History]

Space Florida hopes to recruit commercial space companies to perform launches and landings from the Shuttle Landing Facility. The organization has reached out to suborbital launch company XCOR Aerospace, as well as orbital spaceship builders Sierra Nevada Space Systems, Boeing and Space Exploration Technologies Corp. (SpaceX), and has high hopes many of these companies will establish operations at Kennedy Space Center.

"It's our job to make it a commercial entity ?we're excited for the challenge," Jim Kuzma, senior vice president and chief operating officer of Space Florida, told SPACE.com.

NASA itself may prove to be a customer of the facility when it starts launching its new heavy-lift rocket, the Space Launch System, and Orion spacecraft, in coming years. Under the new arrangement, NASA is no longer shouldering the everyday cost of running the Shuttle Landing Facility ? Florida is ? so if NASA uses the facility it will have to pay for it like any other customer.

"It's exciting for Florida," Kuzma said. "We think the work force is here, the understanding of the needs of the space industry is here."

Andrew Nelson, chief operating officer of XCOR Aerospace, which hopes to begin launching tourists to the edge of space on its Lynx vehicle soon, agreed.

"The workforce is incredible here," he said. "There's just something in the DNA here."

XCOR said it was attracted to the idea of launching flights out of Kennedy Space Center in part because the Space Coast lures so many tourists ? it's about an hour's drive from the tourist Mecca of Orlando.

"There are 30 million tourist visitors a year here," Nelson told SPACE.com. "A few are going to want to fly to space."

Follow Clara Moskowitz on Twitter?and Google+. Follow us?@Spacedotcom, Facebook?and Google+. Original article on?SPACE.com.

Copyright 2013 SPACE.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/nasa-space-shuttle-runway-gets-life-commercial-spaceport-115756289.html

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Paula Deen, Proposition 8, and the sometimes-nuance of bigotry (Americablog)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/315912495?client_source=feed&format=rss

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How Gazprom's $1 trillion dream has fallen apart

By Vladimir Soldatkin

MOSCOW (Reuters) - Zoya Danilina, who owns some 700 shares in Gazprom , says investors don't have to look far to understand that Russia's most powerful company has lost its way.

Danilina remembers when her shares were worth over 300 roubles each. Now they fetch about 100 roubles.

"There have been much better days, when tables were served with black and red caviar," she said on the sidelines of Gazprom's annual general meeting in Moscow on Friday, looking at a plate of boiled buckwheat, a popular staple food in Russia.

In the caviar era, Gazprom head Alexei Miller, a close ally of President Vladimir Putin, was overseeing a company with the world's third-largest market value at $360 billion. In 2007, he promised to boost it to $1 trillion.

Fast forward several years and Gazprom, still the world's largest gas producer and holder of 15 percent of global gas reserves, is worth $77 billion and could fall further as it faces a series of setbacks.

The biggest blow came from a shale gas revolution that has unlocked vast reserves in the United States.

U.S. prices have crashed, closing America as a prospective market for Gazprom, diverting cheaper liquefied natural gas (LNG) cargoes not needed in the United States to Europe, undermining Gazprom's position in its core market.

Europe, tied to Gazprom by a Soviet-built pipeline network, has balked at its contracts that tie gas prices to more expensive oil.

Last year, Miller was forced to offer billions of dollars in what Gazprom described as "rebates" to European buyers.

On Thursday, Germany's RWE said it won an arbitration case against Gazprom, which further loosened the price link to oil and raised the prospect of more price concessions.

Gazprom expects its 2013 earnings to fall by 10 percent, marking a second yearly decline.

The stock market now values Gazprom - the world's third-biggest company by earnings behind ExxonMobil and Apple - at only two times its 2012 earnings of $38 billion. That makes it the cheapest large-cap stock on an already cheap Russian market.

LNG, HOME PRICE SETBACKS

Investors could possibly forgive those setbacks if they were confident Gazprom could expand in the fast growing global LNG markets, while charging rising prices at home.

"Our goal is to control around 15 percent of the global market for liquefied natural gas," Miller, 51, told the annual general meeting on Friday.

But such hopes were dealt heavy blows over the past month.

Putin signaled last week the gradual end of Gazprom's monopoly on exports of LNG and opened the way for rivals Novatek and Rosneft to compete for huge new Asian markets.

"We offer to lower restrictions gradually on liquefied natural gas exports," Putin said in a speech at an economic forum in St Petersburg, both his and Miller's hometown.

Putin also said that monopolies would be able to raise prices only in line with inflation, reducing hopes for much higher returns on the domestic market.

Gazprom's domestic industrial customers pay $114 per 1,000 cubic meters - little more than half of the $201 it receives for exports after being adjusted for transportation and duties.

"Investors are structurally underweight Gazprom as they do not believe in significant change at the company," said Kingsmill Bond, chief strategist at Sberbank Investment Research in Moscow.

POLITICAL TOOL

Under Miller, hired by Putin in 2001, Gazprom often served as a Kremlin political tool, as described by EU officials.

"The Kremlin has decided that Gazprom is part of Russia's national security and geopolitics - not a commercial company," said Chris Weafer, founder of Macro Advisory, a Russia-focused consultancy.

"We are going back to Soviet days, when Gazprom was a government ministry. The market is valuing it like a ministry."

Using Gazprom as a weapon has proved to be a double-edged sword, poisoning relations with Ukraine, the transit route for most of Gazprom's Europe-bound gas, after several pricing disputes, which cut gas flows to Europe during several winters.

Gazprom is now investing billions of dollars in new export routes to circumvent is ex-Soviet neighbor - Nord Stream to Germany and the still-to-be built South Stream to Italy.

Investors fear those projects may never pay out.

Finally, Gazprom has failed to sign a supply deal with China, the world's largest energy market, despite first signing a memorandum of understanding as long ago as 2006.

Should the deal be signed before the end of the year, it may still not be enough to revive the appetite of investors, who have long criticized Gazprom's for overspending.

"The mega-projects will guarantee rapid growth in costs, while future revenues are absolutely uncertain," said Mikhail Korchemkin of consultancy East European Gas Analysis.

(Corrects to one trillion dollars from one billion in fourth par)

(Additional reporting by Denis Pinchuk and Douglas Busvine; Editing by Dmitry Zhdannikov and Jane Baird)

Source: http://news.yahoo.com/gazproms-1-trillion-dream-fallen-apart-181422124.html

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Former Tesco chairman says turnaround could take three years

LONDON (Reuters) - A former chairman of Tesco , the world's No.3 retailer, said that restoring the store group's fortunes could take up to three years and appealed to investors to give Chief Executive Phil Clarke sufficient time.

Once one of the most consistent British companies in terms of earnings growth, Tesco, which trails France's Carrefour and U.S. group Wal-Mart by annual sales, has had a particularly testing year.

In April the firm posted its first profit fall in two decades, wrote down the value of its global operations by $3.5 billion and confirmed plans to exit its loss-making U.S. business Fresh & Easy.

"We're all very sad in this room to see the legacy that Terry Leahy (CEO from 1997 to 2011) left," Ian MacLaurin told shareholders on Friday at the firm's annual meeting.

"It is a very sad situation - your enormous writedowns, (and) the situation in America," said MacLaurin, who chaired Tesco from 1985 to 1997.

MacLaurin said Tesco's board and shareholders had to counter "an age of short-termism" by taking a long-term view and giving Clarke - who took over from Leahy in March 2011 - and his team time to fix things.

"This job is going to be probably two or three years," he said.

Tesco avoided a rebellion from investors over executive pay at the AGM.

Some 95.2 percent of shareholders who voted at the meeting backed the firm's executive pay report, even though advisory group Pensions Investment Research Consultants (Pirc) had called on investors to vote against it in protest at what it regarded as excessive payoffs to two departed executives.

Tesco paid Tim Mason, the former boss of Fresh & Easy, and Richard Brasher, ousted as the head of the UK business in March 2012, "liquidated damages" of 1.68 million pounds ($2.6 million) and 1.3 million pounds respectively in the 2012-13 year. ($1 = 0.6577 British pounds)

(Reporting by James Davey, Editing by Rosalba O'Brien)

Source: http://news.yahoo.com/former-tesco-chairman-says-turnaround-could-3-years-140716181.html

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Hospitals seek high-tech help for hand hygiene

RICHMOND HEIGHTS, Mo. (AP) ? Hospitals have fretted for years over how to make sure doctors, nurses and staff keep their hands clean, but with only limited success. Now, some are turning to technology ? beepers, buzzers, lights and tracking systems that remind workers to sanitize, and chart those who don't.

Health experts say poor hand cleanliness is a factor in hospital-borne infections that kill tens of thousands of Americans each year. The U.S. Centers for Disease Control and Prevention in Atlanta estimates that one of every 20 patients in U.S. hospitals gets a hospital-acquired infection each year.

"We've known for over 150 years that good hand hygiene prevents patients from getting infections," said Dr. John Jernigan, an epidemiologist for the CDC. "However, it's been a very chronic and difficult problem to get adherence levels up as high as we'd like them to be."

Hospitals have tried varying ways to promote better hygiene. Signs are posted in restrooms. Some even employ monitors who keep tabs and single out offenders.

Still, experts believe hospital workers wash up, at best, about 50 percent of the time. One St. Louis-area hospital believes it can approach 100 percent adherence.

Since last year, SSM St. Mary's Health Center in the St. Louis suburb of Richmond Heights, Mo., has been the test site for a system developed by Biovigil Inc., of Ann Arbor, Mich. A flashing light on a badge turns green when hands are clean, red if they're not. It also tracks each hand-cleaning opportunity ? the successes and the failures.

The failures have been few at the two units of St. Mary's where the system is being tested, the hospital said. One unit had 97 percent hand hygiene success, said Dr. Morey Gardner, the hospital's director of infection disease and prevention. The other had 99 percent success.

"The holy grail of infection prevention is in our grasp," Gardner said.

The Biovigil system is among many being tried at hospitals. A method developed by Arrowsight, based in Mt. Kisco, N.Y., uses video monitoring. It is being used in intensive care units at North Shore University Hospital in Manhasset, N.Y., and the University of California San Francisco Medical Center.

Akron, Ohio-based GOJO Industries, maker of Purell hand sanitizer, has developed an electronic compliance monitoring system using wireless technology to track when soap and hand sanitizer dispensers are used. The SmartLink system gives the hospital data on high- and low-compliance areas. The company said it has installed the system at several hospitals around the country, but didn't say how many.

HyGreen Inc.'s Hand Hygiene Reminder System was developed by two University of Florida doctors. The Gainesville, Fla., company now features two systems used in seven hospitals, including Veterans Administration hospitals in Chicago, Wilmington, Del., and Wilkes-Barre, Pa.

One is similar to Biovigil's green badge method. In HyGreen's, a wall-mounted hand wash sensor detects alcohol on the hands. The badge includes an active reminding system. Unclean hands create a warning buzz. If the buzz sounds three times, the worker is noted for noncompliance.

HyGreen spokeswoman Elena Fraser said that because some hospitals are moving away from alcohol-based sanitizers, HyGreen offers a second system. A touch of the sanitizer dispenser clears the worker to interact with a patient. If the worker shows up at the patient bed without hand-cleaning, the series of warning buzzes begins.

Fraser said hospital infections have dropped 66 percent at units of Miami Children's Hospital where the badge system has been implemented.

Nurses using the Biovigil system at St. Mary's near St. Louis wear a badge with changeable colored lights. A doorway sensor identifies when the nurse enters a patient's room, and the badge color changes to yellow.

The nurse washes his or her hands and places them close to the badge. A sensor in the badge detects chemical vapors from the alcohol-based solution. If hands are clean, the badge illuminates a bright green hand symbol.

If the nurse fails to sanitize, the badge stays yellow and chirps every 10 seconds for 40 seconds, then flashes red. Once the flashing red starts, the nurse has another 30 seconds to wash up, otherwise the badge turns solid red, denoting non-compliance. Either way, each instance is tracked by a computer. The hospital can track each individual's compliance.

Registered Nurse Theresa Gratton has helped lead the effort toward hand cleanliness at St. Mary's. She heard about the Biovigil system in early 2012 and convinced the hospital to give it a try.

Gratton said patients are aware of the risk of infection and frequently inquire about whether caregivers have washed their hands. She said the badge relieves their anxiety.

Bill Rogers, a 65-year-old retiree recuperating at St. Mary's from back surgery and a heart scare, agreed.

"The first thing I noticed up here was the badges," Rogers said. "It is comforting for me to know their hands are clean as soon as the badge beeps and it goes from yellow to green."

St. Mary's is expanding the Biovigil system later this year to other units of the hospital and to employees other than nurses, though details are still being worked out, Gardner said. Eventually, the system may be expanded to SSM's seven other St. Louis-area hospitals, he said.

Biovigil's chief client officer, Brent Nibarger, said customers won't buy the system but will pay a subscription fee of about $12 a month per badge.

The CDC's Jernigan said the high-tech systems can only help.

"For a health care worker, keeping their hands clean is the single most important thing they can do to protect their patients," Jernigan said.

Source: http://news.yahoo.com/hospitals-seek-high-tech-help-hand-hygiene-071012525.html

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